Integrin Alpha2b anticorps (FITC)

N° du produit ABIN119841

Cet anticorps anti-Integrin Alpha2b est un anticorps Rat Monoclonal détectant Integrin Alpha2b dans FACS. Adapté pour Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour Integrin Alpha2b anticorps (FITC) (ABIN119841)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: MWReg30

Détail du produit anti-Integrin Alpha2b anticorps (FITC)

Specificité: This antibody recognises the integrin alpha IIb subunit CD41.

Purification: Protein G affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: use 10 μL of neat - 1/10 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo . We recommend the use of ABIN119839 for use in functional studies.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide and 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Integrin Alpha2b (FITC) (ABIN119841)

Zanzinger, Schellack, Nausch, Cerwenka: "Regulation of triggering receptor expressed on myeloid cells 1 expression on mouse inflammatory monocytes." dans: Immunology, Vol. 128, Issue 2, pp. 185-95, (2009) (PubMed).

Larson, Watson: "Regulation of proplatelet formation and platelet release by integrin alpha IIb beta3." dans: Blood, Vol. 108, Issue 5, pp. 1509-14, (2006) (PubMed).

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41 / ITGA2B

Sujet: CD41 is expressed on platelets and megakaryocytes and forms a heterodimer with CD61. CD41/CD61 is important for platelet adhesion and aggregation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

ID gène: 16399

NCBI Accession: NP_034705

UniProt: Q9QUM0

Pathways: Integrin Complex